Revealed: maker of Wegovy ‘skinny jab’ is funding NHS weight-loss services | Pharmaceuticals industry

Revealed: maker of Wegovy ‘skinny jab’ is funding NHS weight-loss services | Pharmaceuticals industry

The pharmaceutical company that makes Wegovy slimming jabs is funding the expansion of weight-loss services across England as it seeks to boost sales of its obesity drugs, the Observer can reveal.

Novo Nordisk is paying the salaries of staff on NHS obesity teams and financing the launch and redesign of services, including giving £206,000 to a health partnership to transform its treatment of obesity. The Danish firm also has financial links to the co-chair of an NHS England weight management advisory group, and paid her almost £50,000 in lecture, consulting and other fees in just two years.

Novo Nordisk’s funding arrangements are under the spotlight after an Observer investigation in March found it had paid £21.7m to UK health organisations and professionals in three years before the approval of its Wegovy injections for NHS use.

In some cases, recipients of the funding went on to praise Wegovy or support its approval for use on the NHS without always making their links to Novo clear. This weekend, the National Institute for Health and Care Excellence (Nice) said an internal inquiry had found that some of those who advised it on the use of Wegovy in the NHS had not properly declared their interests.

Now further documents reveal how Novo Nordisk has been granted a potential role in shaping obesity treatment through partnerships with NHS trusts, pharmacies and GPs to provide training and funding.

In one case, the company is paying £206,000 to an integrated care system to help it “transform” its specialist obesity services and “reduce unnecessary barriers” to treatment.

Novo’s money is paying for two “dedicated” staff members and “independent facilitation support” for a partnership with Mid and South Essex NHS trust and local councils, which aims to provide a blueprint for transforming other weight loss services across the country.

In another partnership, Novo Nordisk has agreed to fund a weight management nurse specialist to work at the Somerset NHS foundation trust, which it has also partnered with to design an online weight management course for patients.

A separate initiative with the National Pharmacy Association aims to “upskill pharmacists” in obesity medicine and help them launch new weight management services. Novo is providing support with “financial tracking and ensuring delivery of outcomes” and funding to develop resources for the two-year project.

Novo Nordisk also has close links to the co-chair of an NHS England advisory group on specialist weight management services. Prof Rachel Batterham was appointed to the unpaid NHS role in 2021 despite a longstanding relationship with the company. Disclosure UK records – which detail payments to healthcare professionals such as consulting, lecture and conference fees – show she was paid £16,306 in “service fees” by Novo in 2020 and £33,560 in 2021. She was also an investigator on a Novo Nordisk-sponsored trial of its Wegovy (semaglutide) injections and subsequently described the treatment as a “gamechanger”.

NHS England is understood to have been aware of Batterham’s link to Novo when it appointed her to the group, which was set up to advise on the allocation of resources, post-Covid recovery and the possible expansion of specialist weight-loss services. It said the group had not yet provided any formal advice due to delays receiving funding, and had not formally requested declarations of interest.

The National Institute for Health and Care Excellence offices
The National Institute for Health and Care Excellence said an internal inquiry had found that some of those who advised it on the use of Wegovy in the NHS had not properly declared their interests. Photograph: Paul Lawrenson/Alamy

Batterham, who received an OBE last year for her services to people affected by obesity, said she was “no longer working with Novo Nordisk”, having ended her paid consultancy work with the company in December, and had always been transparent about her affiliations, including disclosing her conflicts of interest to NHS England. She added that her “globally recognised research” had focused on “all aspects of weight-management” and that she worked with the NHS and companies “to help improve and grow our collective clinical understanding”.

There is no suggestion the partnerships break any rules, which permit industry payments to the health sector provided they are transparently declared and comply with policies on bribery and anti-corruption. Wegovy injections have been safety-tested and approved for NHS use, with studies suggesting they can help people lose 15{1668a97e7bfe6d80c144078b89af180f360665b4ea188e6054b2f93f7302966b} of body weight. More than a quarter of adults in England are classed as obese, and expanding specialist services could help more people access vital treatment.

But critics say the arrangements could give Novo Nordisk a role in shaping services that use its weight-loss drugs, raising questions about conflicts of interest. A document about its partnership with the National Pharmacy Association is explicit about the potential benefits, saying in a section titled “benefit to Novo Nordisk” that “an increase in the availability of weight-management services may result in an increase in the prescribing of anti-obesity medications”.

David Rowland, director of the Centre for Health and the Public Interest thinktank, said “clear safeguards” were needed to “prevent the financial interests of pharmaceutical companies from polluting services provided to patients”. He said health organisations were often struggling for funding but needed to consider the “trade-offs” carefully. “If companies are not seeing prescriptions of a particular drug, where does that leave them in terms of their interest in funding these services?” he added.

Dr Margaret McCartney, an expert in conflicts of interest in healthcare and senior lecturer at the University of St Andrews School of Medicine, said drug firms should “not be anywhere near the design of NHS services or decisions about cost-effectiveness” and called for “independent scrutiny”. She said international evidence showed that financial conflicts of interest can lead to “more expensive and poorer quality healthcare”.

It is not the first time concerns have been raised about Novo’s links to health organisations. In January, the Royal College of Physicians (RCP) received a complaint from a doctor who said the college’s association with a Novo Nordisk-funded fellowship scheme gave it a “veneer of respectability”. The year-long programme, which was supposed to launch this June, would have seen fellows paid £60,000 by Novo to work in NHS obesity teams, with aims including “leading the establishment of new weight management services”. The RCP said Novo’s relationship with fellows would have been “arm’s length”, and that it “played no part in drafting the fellowship job description or in the selection of the centres or the candidates”.

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Concerns are also understood to have been raised within the Royal College of GPs (RCGP), which received more than £400,000 from Novo Nordisk between 2019 and 2021, according to Disclosure UK records, and launched an obesity “leadership programme” with the company in 2021.

A key benefit for Novo of that collaboration – which aimed to train 20 GPs to become leaders in obesity care and was financed with £154,229 of corporate funds – was that it could “enhance Novo Nordisk’s reputation nationally”, documents show. The RCGP said it worked with a “variety of partners” to support obesity care, adding that it had a “strict sponsorship policy” and that its resources for GPs did not promote any particular drugs.

In recent days, both the royal colleges have cut ties with Novo and returned outstanding funding after its two-year suspension by the Association of the British Pharmaceutical Industry (ABPI) over “serious breaches” of industry code. Novo had sponsored webinars for health professionals that amounted to a “disguised promotional campaign” of another of its weight-loss drugs, the ABPI said on 16 March. “Having considered the case and requesting a further detailed audit of Novo Nordisk’s compliance processes, the ABPI board decided to suspend Novo Nordisk from ABPI membership,” it said.

Wegovy injector pens
Wegovy, a brand name for semaglutide, is designed to suppress appetite. Photograph: Jim Vondruska/Reuters

This weekend, Novo Nordisk said details of its health service partnerships had been “unfairly presented” and that they were “standard industry practice within the industry code … in line with work other pharmaceutical companies do to support the NHS and healthcare organisations”. It added: “We disclose all partnerships, contracts, grants, donations and sponsorships to UK-based professionals and organisations transparently.”

Organisations that partnered with Novo told the Observer the funding had not influenced decision-making. Mid and South Essex integrated care system said its project was now under review and did not include “any decision-making around use of medicines”. Somerset NHS Foundation Trust said Novo had no influence over “purchasing, prescribing and dispensing” decisions, and the trust had “a robust conflicts of interest policy”. The National Pharmacy Association said it had vetted all materials used in its project with Novo and they did not recommend any particular product or treatment.

In a separate development, an investigation by Nice this weekend concluded that two organisations that advised its committee assessing Wegovy for the NHS failed to fully disclose payments from Novo. Nice said the Association for the Study of Obesity and the Royal College of Physicians breached its policy. An expert who gave evidence, Prof John Wilding, did not.

The RCP said it should have volunteered details of funding from Novo but that it had not influenced its evidence, and said it was now looking at steps to increase transparency.

The ASO said it would seek “clarity” about the watchdog’s findings, adding that it had “always acted with good intention” and “put the outcomes of people living with obesity at front and centre”. It previously said it had properly disclosed funding from Novo.

Nice said the breaches “did not involve the individuals who developed Nice’s recommendations”. “The failures to declare all interests did not have a material effect on the outcome on the guidance Nice produced,” it added.

Textile Recycler Circ Closes $25 Million Funding Round From Avery Dennison, Zalando

Textile Recycler Circ Closes  Million Funding Round From Avery Dennison, Zalando

Fiber-to-fiber recycling tech business Circ has shut a $25 million spherical of funding backed by European online fashion giant Zalando, and world resources science organization Avery Dennison. Korean company Youngone also joined the round.

The latest injection of money follows a $30 million Collection B spherical past July, which was joined by Bill Gates-backed Breakthrough Strength Ventures, American textile maker Milliken & Organization, and Spanish rapid-trend big Inditex, father or mother firm of Zara, among the other folks.

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“Transforming the manner economic system requires management from influential players in the textile marketplace, the money group, as well as technologies innovators,” mentioned main executive officer Peter Majeranowski.

“The Circ crew, which involves not only our employees but also our traders and partners, encompasses a various team of retail, producing and engineering leaders throughout the U.S., Europe and Asia. We share a typical watch that a cleanse long term for the manner field is not only possible but also essential for humanity. With each individual funding round and expansion in our husband or wife base, we come to be far more capable of ending the expensive and preventable cycle of garment waste.”

The most up-to-date spherical will proceed to accelerate Circ’s engineering enlargement as it scales up to industrial-degree facilities and enable the business produce its to start with shopper solutions to market.

Majeranowski launched Circ in 2011, and has made a hydrothermal procedure to split down textiles, recuperate cotton and polyester while sustaining its integrity and transform them into new components.

Circ’s tech can also separate and recover poly-cotton blends, so far a big challenge for the field. Whilst poly-cotton blends account for a substantial chunk of the outfits designed currently, much less than 1 {1668a97e7bfe6d80c144078b89af180f360665b4ea188e6054b2f93f7302966b} is at present recycled.

“With the investment in Circ, we are contributing to an emerging infrastructure for circularity that will eventually assist the fashion marketplace at big, to shift away from a just take-make-waste model,” explained Zalando co-main executive officer David Schneider. “We want to be a sustainable trend system with a internet-optimistic impression for men and women and the earth, and we are energized about the probable of Circ to add to this vision.”

“The time for round techniques and their enabling technologies is now. Using smart labeling in clothes, Avery Dennison is working with Circ and other offer chain associates to give a alternative for the just take-again and sorting of waste at scale,” reported Michael Colarossi, Avery Dennison’s vice president of innovation and sustainability.

Circ’s fiber-to-fiber tech aims to lessen the want for virgin textiles in the offer chain. Getting those textiles again into circular production will choose petroleum and tree-primarily based merchandise out of the fashion program, Circ states. According to Breakthrough Strength Ventures, the textiles business is believed to account for extra than 1 billion metric tons of carbon emissions, the major part of which comes from raw resources.

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Securities finance industry news | BNP Paribas takes part in Series C funding round for AccessFintech

Securities finance industry news | BNP Paribas takes part in Series C funding round for AccessFintech

BNP Paribas is to take part in a Series C fund round for AccessFintech, the fintech organization headed by Roy Saadon.

The expenditure is staying created by BNP Paribas’s Securities Companies device, the bank’s put up-trade arm.

The Paris-primarily based banking team indicates that this investment will empower it to present its corporate and institutional banking shoppers with the hottest technological know-how, information and workflow equipment in an effort to shorten settlement cycles.

Clientele will also be able to boost operational performance via AccessFintech’s Synergy details collaboration network, BNP Paribas says.

Synergy will help industry individuals cut down collateral demands and compress transaction
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costs as a result of data collaboration, accelerated workflows and AccessFintech’s cloud-centered strategy to info governance and normalisation.

Synergy also helps world-wide financial institutions, broker-sellers, custodians, asset professionals and hedge funds with regulatory compliance through mutually managed network alternatives.

The Sequence C funding spherical was led by WestCap. In addition to its Series B fundraising led by Dawn Capital, AccessFintech has now secured investment decision from the world’s biggest economical establishments like JPMorgan, Goldman Sachs, Citi, Bank of The us and BNY Mellon.

Alongside these investors, BNP Paribas’s participation will be utilized to accelerate AccessFintech’s advancement as it expands its collaborative knowledge administration community to additional markets.

Bruno Campenon, world wide head of banking companies, brokers and corporates of Securities Products and services, at BNP Paribas, states: “This investment is element of our technique to partner with modern know-how companies to broaden and digitalise our featuring and give our shoppers accessibility to the hottest systems.

“AccessFintech’s methods will deliver concrete added benefits to our purchasers – and the sector as a full – through greater operational efficiency and optimised hazard management. We are enthusiastic to participate in this initiative and enable the financial industry evolve its running model.”

Roy Saadon, CEO of AccessFintech, opinions: “We are delighted with the aid BNP
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Paribas is extending to the vital purpose we provide of trusted knowledge governance infrastructure.

“The innovation we are offering in the facts collaboration arena is a great enhance to BNP Paribas’s force to generate the sector ahead. Their knowing of disruptive technological know-how, coupled with our shared eyesight, will permit AccessFintech to grow and execute the next stage of our progress.”

Gov. Wolf Announces New Funding to Increase Textile Industry Workers in the Philadelphia Region

Gov. Wolf Announces New Funding to Increase Textile Industry Workers in the Philadelphia Region

Waynesboro, PA – Governor Tom Wolf introduced $189,000 in new funding for Delaware Valley Industrial Resource Middle